FGL1 (Fibrinogen-Like Protein 1) is a secreted protein primarily produced by the liver. It belongs to the fibrinogen-related protein family and plays roles in liver regeneration, metabolic regulation, and immune modulation. FGL1 is also known as a major ligand for the immune checkpoint receptor LAG-3, contributing to immune suppression in the tumor microenvironment and making it relevant in cancer biology and immunotherapy research.