The human CD155 extracellular domain is consisted of amino acids 1-343 with a human IgG1-Fc tag at the N-terminus. CD155, also known as Poliovirus receptor (PVR), is a protein that in humans is encoded by the CD155 gene. It is a transmembrane protein that belongs to the immunoglobulin superfamily. CD155 is expressed on the surface of various normal tissues, including brain, placenta, lung, liver, kidney, and heart. It functions as a receptor for poliovirus, measles virus, and several other viruses that cause a disease in humans. Additionally, CD155 has an important role in the immune system, where it functions in the regulation of T cell activation and differentiation. Dysfunction of CD155 is associated with the pathology of many diseases, including viral infections, autoimmune disorders, and cancer.

CD155 Datasheet

CD155 MSDS