Aurora Ni-TED RF (Rapid Flow) Resin is an affinity chromatography resin that binds TED ligands chelated with nickel ions to agarose microspheres. Due to the strong chelating ability of TED on nickel ions, Ni-TED can tolerate high concentrations of EDTA and DTT. It is often used to conveniently purify secreted histagged recombinant proteins straight from cell culture medium.