SOS1 is a guanine nucleotide exchange factor (GEF) for RAS proteins, which are membrane associated proteins involved in various signaling pathways. RAS proteins are activated by GEF-facilitated GDP exchange for GTP, and inactivated by GTP hydrolysis. RAS signaling is upregulated in many different cancers, thus making RAS activation via SOS1 interaction a promising target for cancer therapy.

SOS 1 (Tagless) Information

SOS 1 (Tagless) MSDS