
Human DNA polymerase theta protein is an enzyme encoded by the POLQ gene. It belongs to the family of DNA polymerases, which are enzymes involved in DNA replication and repair processes.
POLQ is a specialized DNA polymerase with unique characteristics. Unlike other polymerases involved in DNA replication, POLQ is primarily associated with the repair of DNA double-strand breaks (DSBs). DSBs are severe types of DNA damage that can lead to genomic instability and are associated with cancer development.